國立中興大學食品暨應用生物科技學系

Wei-Jan Wang , Yeh Chen , Wen-Chi Su , Yen-Yi Liu , Wan-Jou Shen, Wei-Chao Chang , Sheng-Teng Huang , Cheng-Wen Lin , Yu-Chuan Wang , Chia-Shin Yang , Mei-Hui Hou, Yu-Chi Chou , Yang-Chang Wu , Shao-Chun Wang , Mien- Chie Hung(第一作者)

Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2.

Journal of Food Biochemistry

2022

SCI期刊

Chen-Shiou Wu , Hsiu-Mei Chiang , Yeh Chen , Chung-Yu Chen , Hsiao-Fan Chen , Wen-Chi Su , Wei-Jan Wang , Yu-Chi Chou , Wei-Chao Chang , Shao- Chun Wang , Mien-Chie Hung

Prospects of Coffee Leaf against SARS-CoV-2 Infection.

International Journal of Biological Sciences.

2022

SCI期刊

Hsiao-Fan Chen , Po-Ren Hsueh , Yen-Yi Liu , Yeh Chen , Sui-Yuan Chang , Wei-Jan Wang , Chen-Shiou Wu , Ya-Min Tsai , Yu-Shu Liu , Wen-Chi Su , Yu- Chi Chou , Mien-Chie Hung

Disulfiram blocked cell entry of SARSCoV-2 via inhibiting the interaction of spike protein and ACE2.

American Journal of Cancer Research .

2022

SCI期刊

Chien-Yi Ho, Jia-Xin Yu,Yu-Chuan Wang, Yu-Chuan Lin, Yi-Fang Chiu, Jing- Yan Gao, Shu-Jung Lai, Ming-Jen Chen, Wei-Chien Huang, Ni Tien* and Yeh Chen*(通訊作者)

A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism.

nternational Journal of Molecular Sciences

18;23(10):5669.

2022

SCI期刊

Tzu-Ping Ko, Yu-Chuan Wang, Chia-Shin Yang, Mei-Hui Hou, Chao-Jung Chen, Yi-Fang Chiu,and Yeh Chen* (通訊作者)

Crystal structure and functional implication of bacterial STING.

Nature Communications

Jan 10;13(1):26.1-13.

2022

SCI期刊

Ni Tien、Chien Yi Ho、Shu Jung Lai、Yu Chuan Lin、Chia Shin Yang、Yu Chuan Wang、Wei Chien Huang、Yeh Chen*、Jui Jen Chang (通訊作者)

Crystal structure of the capsular polysaccharide-synthesis enzyme CapG from Staphylococcus aureus.

Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS .

2021

SCI期刊

Yeh Chen, WC-Huang, CS-Yang, FJ-Cheng, YF-Chiu, HF-Chen, TK Huynh, CF-Huang, CH- Chen, HC-Wang, MC-Hung (第一作者)

Screening strategy of TMPRSS2 inhibitors by FRET-based enzymatic activity for TMPRSS2-based cancer and COVID-19 treatment

American Journal of Cancer Research

11(3):827-836.

2021

SCI期刊

Fang-Ju Cheng ,Thanh-Kieu Huynh ,Chia-Shin Yang ,Dai-Wei Hu,Yi-Cheng Shen, Chih-Yen Tu,Yang-Chang Wu, Chih-Hsin Tang, Wei-Chien Huang *, Yeh Chen*, and Chien-Yi Ho* (通訊作者))

Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection.

Nutrients

16;13(8):2800.

2021

SCI期刊

Bo-Wei Wang , Chih-Hao Huang , Liang-Chih Liu, Fang-Ju Cheng , Ya-Ling Wei, Yueh-Ming Lin , Yu-Fei Wang , Ching-Ting Wei , Yeh Chen*, Yun-Ju Chen* and Wei-Chien Huang*

Pim1 Kinase Inhibitors Exert Anti-Cancer Activity Against HER2-Positive Breast Cancer Cells Through Downregulation of HER2.

Front. Pharmacol

29;12:614673.

2021

SCI期刊

Sheng-Teng Huang†,Yeh Chen†,Wei-Chao Chang†,Hsiao-Fan Chen ,Hsiang- Chun Lai ,Yu-Chun Lin,Wei-Jan Wang,Yu-Chuan Wang,Chia-Shin Yang ,Shao- Chun Wang and Mien-Chie Hung (第一作者)

Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) Infection.

Viruses

2021, 13, 826.

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