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Chen, Yeh
Associate Professor
Name：Chen, Yeh  Teacher
Title：Associate Professor
ResearchRoom：Structural Biology Lab
Tel：04-2284-0385#3190
Research：Structural Biology、Biomacromolecule X-ray Crystallography、 Structure-Based Drug Development

Degree
1994/09/01~1998/06/30
China Medical University, Taiwan Department of Nutrition()
 
1998/09/01~2000/06/30
National Defense University, Taiwan Department and Graduate Institute of Biochemistry()
 
2000/07/01~2005/07/31
National Chung Hsing University, Taiwan Graduate Institute of Biochemistry()
 

Experience
2007/04/01~2009/10/15
Institute of Biochemistry, Academia Sinica-Postdoctoral Researcher
 
2009/10/16~2015/02/15
Department of Biochemistry, HungKuang University-assistant Professor
 
2015/02/16~2019/12/31
Department of Biochemistry, HungKuang University-Associate Professor
 
2020/02/01~2023/01/31
Institute of Translational Medicine and New Drug Development， Chinese Medical University-Associate Professor
 

| Article | Glory | 
Date
Class
Author
Topic
PeriodicalName
Page
2022
SCI期刊
Ni Tien、Chien Yi Ho、Shu Jung Lai、Yu Chuan Lin、Chia Shin Yang、Yu Chuan Wang、Wei Chien Huang、Yeh Chen*、Jui Jen Chang (通訊作者)
Crystal structure of the capsular polysaccharide-synthesis enzyme CapG from Staphylococcus aureus.
Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS .
2022
SCI期刊
Wei-Jan Wang , Yeh Chen , Wen-Chi Su , Yen-Yi Liu , Wan-Jou Shen, Wei-Chao Chang , Sheng-Teng Huang , Cheng-Wen Lin , Yu-Chuan Wang , Chia-Shin Yang , Mei-Hui Hou, Yu-Chi Chou , Yang-Chang Wu , Shao-Chun Wang , Mien- Chie Hung(第一作者)
Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2.
Journal of Food Biochemistry
2022
SCI期刊
Chen-Shiou Wu , Hsiu-Mei Chiang , Yeh Chen , Chung-Yu Chen , Hsiao-Fan Chen , Wen-Chi Su , Wei-Jan Wang , Yu-Chi Chou , Wei-Chao Chang , Shao- Chun Wang , Mien-Chie Hung
Prospects of Coffee Leaf against SARS-CoV-2 Infection.
International Journal of Biological Sciences.
2022
SCI期刊
Hsiao-Fan Chen , Po-Ren Hsueh , Yen-Yi Liu , Yeh Chen , Sui-Yuan Chang , Wei-Jan Wang , Chen-Shiou Wu , Ya-Min Tsai , Yu-Shu Liu , Wen-Chi Su , Yu- Chi Chou , Mien-Chie Hung
Disulfiram blocked cell entry of SARSCoV-2 via inhibiting the interaction of spike protein and ACE2.
American Journal of Cancer Research .
2022
SCI期刊
Chien-Yi Ho, Jia-Xin Yu,Yu-Chuan Wang, Yu-Chuan Lin, Yi-Fang Chiu, Jing- Yan Gao, Shu-Jung Lai, Ming-Jen Chen, Wei-Chien Huang, Ni Tien* and Yeh Chen*(通訊作者)
A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism.
nternational Journal of Molecular Sciences
18;23(10):5669.
2022
SCI期刊
Tzu-Ping Ko, Yu-Chuan Wang, Chia-Shin Yang, Mei-Hui Hou, Chao-Jung Chen, Yi-Fang Chiu,and Yeh Chen* (通訊作者)
Crystal structure and functional implication of bacterial STING.
Nature Communications
Jan 10;13(1):26.1-13.
2021
SCI期刊
Fang-Ju Cheng ,Thanh-Kieu Huynh ,Chia-Shin Yang ,Dai-Wei Hu,Yi-Cheng Shen, Chih-Yen Tu,Yang-Chang Wu, Chih-Hsin Tang, Wei-Chien Huang *, Yeh Chen*, and Chien-Yi Ho* (通訊作者))
Hesperidin Is a Potential Inhibitor against SARS-CoV-2 Infection.
Nutrients
16;13(8):2800.
2021
SCI期刊
Bo-Wei Wang , Chih-Hao Huang , Liang-Chih Liu, Fang-Ju Cheng , Ya-Ling Wei, Yueh-Ming Lin , Yu-Fei Wang , Ching-Ting Wei , Yeh Chen*, Yun-Ju Chen* and Wei-Chien Huang*
Pim1 Kinase Inhibitors Exert Anti-Cancer Activity Against HER2-Positive Breast Cancer Cells Through Downregulation of HER2.
Front. Pharmacol
29;12:614673.
2021
SCI期刊
Sheng-Teng Huang†,Yeh Chen†,Wei-Chao Chang†,Hsiao-Fan Chen ,Hsiang- Chun Lai ,Yu-Chun Lin,Wei-Jan Wang,Yu-Chuan Wang,Chia-Shin Yang ,Shao- Chun Wang and Mien-Chie Hung (第一作者)
Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) Infection.
Viruses
2021, 13, 826.
2021
SCI期刊
Tzu-Ping Ko , Yu-Chuan Wang, Chia-Ling Tsai, Chia-Shin Yang, Mei-Hui Hou and Yeh Chen* (通訊作者)
Crystal structure and functional implication of a bacterial cyclic AMP–AMP–GMP synthetase.
Nucleic Acids Research
49(8),4725-4737.
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